Commercially Available Tissue Models

Last updated: 24 January 2025.
To download a copy of the table, click here.

Disclaimer: This table primarily focuses on reconstructed human tissues. The information provided in this table is sourced from various suppliers and may not be complete or fully accurate. Inclusion of any supplier or product does not imply endorsement or recommendation. Chemically defined medium definition is based on Chary et al. 2022.
Tissue model nameSupplierOrgan/systemTissue detailCell typesChemically defined media*FacilitiesIncluded in OECD Test Guideline?
SkinEthic HBEEpiSkin, L’orealBladderBladder epitheliumImmortalized human bladder epithelial cells (RT-112)YesFrance
Cartilage modelBioSolutionCartilageCartilagePrimary human chondrocytesSouth Korea
3D Osteochondral ModelAlcyomics®CartilageCartilageMesenchymal stem cell-derived chondrocytes and osteoblastsUK
MCTT HCE™BioSolutionEyeCorneal epitheliumPrimary human corneal epithelial cellsSouth KoreaTG 492
SkinEthic™ HCEEpiSkin, L’orealEyeCorneal epitheliumTransformed human corneal keratinocytesYesFranceTG 492, TG 492B
LabCyte CORNEA-MODELJapan Tissue EngineeringEyeCorneal epitheliumPrimary human corneal epithelial cellsNoJapanTG 492
EpiCorneal™MatTekEyeCorneal epitheliumPrimary human corneal epithelial cellsNoUSA/Slovakia
EpiOcular™MatTekEyeCorneal epitheliumPrimary human epidermal keratinocytesNoUSA/SlovakiaTG 492
Retinal Pigment EpitheliumNewcells BiotechEyeRetinal Pigment EpitheliumiPSC-derived retinal pigment cellsUK
RepliGut® PlanarAltis BiosystemsGutSmall Intestine (duodenum, jejunum, iIleum) or Colon (ascending, transverse or descending)Primary human intestinal epithelial cellsUSA
EpiIntestinal™MatTekGutSmall intestine epitheliumPrimary human small intestinal epithelial cellsNoUSA/Slovakia
EpiIntestinal™ FTMatTekGutSmall intestine epithelium and interstitiumPrimary human small intestinal epithelial cells and fibroblastsNoUSA/Slovakia
NuHeart™InvivoSciencesHeartHeart microtissuesiPSC-derived cardiomiocytesUSA
hvCOC, Human Heart-in-a-JarNovoheart™HeartHeart microtissuesiPSC-derived cardiomiocytesCanada
hvCTSNovoheart™HeartHeart microtissuesiPSC-derived cardiomiocytesCanada
EpiKidney™(beta)MatTekKidneyNephron (kidney proximal tubule epithelium)Primary human proximal tubule epithelial cellsNoUSA/Slovakia
aProximate™Newcells BiotechKidneyNephron (kidney proximal tubule epithelium)Primary human proximal tubule epithelial cellsYesUK
Liver modelBioSolutionLiverHepatocytesStem cell-derived liver cellsSouth Korea
Hepatopac®BioIVTLiverHepatocytesPrimary human hepatocytes or immortalized hepatocytes (upcyte®), and stromal cellsNoUK/USA
Hepatomune®BioIVTLiverHepatocytes & Kupfer cellsPrimary human hepatocytes or immortalized hepatocytes (upcyte®), stromal cells and Kupffer cellsUK/USA
3D InSight™ Human Liver MicrotissuesInSpheroLiverHepatocytes & Kupfer cellsPrimary human hepatocytes, stromal cells (hepatic endothelial cells) and Kupffer cellsSwitzerland/USA
TruVivo®LifeNet HealthLiverHepatocytesPrimary human hepatocytes, stromal cells (inc. endothelial cells)USA/Worldwide
EpiLiver™(beta)MatTekLiverHepatocytesPrimary human hepatocytesNoUSA/Slovakia
Dopaminergic neuron modelBioSolutionNervous systemCentral nervous system (brain)Stem cell-derived dopaminergic neuronsSouth Korea
BrainSim®AxoSimNervous systemCentral nervous system (brain)iPSC-derived neurons and glial cells (astrocytes and oligodendrocytes)USA
microBrain™AxoSimNervous systemCentral nervous system (brain)iPSC-derived cortical neurons and glial cells (astrocytes)USA
NerveSim®AxoSimNervous systemPeripheral nervous system (nerves)iPSC derived neurons and glial cells (Schwann cells)USA
SoluOral™BioSolutionOralOral epitheliumOral mucosal epithelial cellsSouth Korea
SkinEthic™ HGEEpiSkin, L’orealOralGingival epitheliumPrimary human gingival keratinocytesYesFrance
SkinEthic™ HO2EEpiSkin, L’orealOralOesophageal epitheliumImmortalized oesophageal epithelial cells (Kyse 510)YesFrance
SkinEthic™ HOEEpiSkin, L’orealOralOral epitheliumImmortalized oral epithelial cells (TR146)YesFrance
EpiGingival™MatTekOralGingival epitheliumPrimary human gingival keratinocytesNoUSA/Slovakia
EpiGingival™ FTMatTekOralGingival epitheliumPrimary human gingival keratinocytes and fibroblastsNoUSA/Slovakia
EpiOral™MatTekOralOral epitheliumPrimary human oral keratinocytesNoUSA/Slovakia
EpiOral™ FTMatTekOralOral epitheliumPrimary human oral keratinocytes and fibroblastsNoUSA/Slovakia
EpiOral™ FT LCMatTekOralOral epitheliumPrimary human oral keratinocytes and Langerhans cellsNoUSA/Slovakia
Islet modelBioSolutionPanchreasStem cells-derived isletsStem cell-derived human islet cellsSouth Korea
3D InSight™ Human Islet MicrotissuesInSpheroPanchreasReaggreated human islet cellsPrimary human islet cellsSwitzerland/USA
SoluAirway™BioSolutionRespiratoryTracheobronchial epitheliumPrimary human tracheal/bronchial epithelial cellsSouth Korea
AlveolAir™EpithelixRespiratoryAlveolar epitheliumAlveolar epithelial cells (type I and II) and endothelial cellsYesSwitzerland
MucilAir™EpithelixRespiratoryNasal, tracheal or bronchial epitheliumPrimary human nasal, tracheal or bronchial epithelial cellsYesSwitzerland
MucilAir™ HFEpithelixRespiratoryNasal, tracheal or bronchial epithelium incl. fibroblastsPrimary human nasal, tracheal or bronchial epithelial cells and fibroblastsYesSwitzerland
SmallAir™ HFEpithelixRespiratorySmall airway (bronchiolar) epitheliumSmall airway epithelial cells and fibroblastsYesSwitzerland
SmallAir™EpithelixRespiratorySmall airway (bronchiolar) epitheliumSmall airway epithelial cellsYesSwitzerland
HiAlvHiLungRespiratoryAlveolar epitheliumiPSC-derived alveolar epithelial cellsJapan
HiTrachHiLungRespiratoryTracheobronchial epitheliumiPSC-derived tracheal epithelial cellsJapan
ImmuLUNG™ImmuONE™RespiratoryAlveolar epitheliumImmortalized human alveolar epithelial cells and alveolar macrophage-likeUK
ALIsensInvitrolizeRespiratoryAlveolar epitheliumImmortalized alveolar epithelial cells (A549), immortalized endothelial cells (EA.hy926), immortalized macrophage-like cells (dTHP-1) and immortalized dendritic-like cells (THP-1)NoLuxemburg
EpiAirway™MatTekRespiratoryTracheobronchial epitheliumPrimary human tracheal/bronchial epithelial cellsNoUSA/Slovakia
EpiAirway™ FTMatTekRespiratoryTracheobronchial epitheliumPrimary human tracheal/bronchial epithelial cells and stromal fibroblastsNoUSA/Slovakia
EpiAlveolar™MatTekRespiratoryAlveolar epitheliumPrimary alveolar epithelial cells (type I and II), pulmonary fibroblasts and pulmonary endothelial cells (possible with immortalized macrophage-like cells, THP-1)NoUSA/Slovakia
EpiNasal™(beta)MatTekRespiratoryNasal epitheliumPrimary human nasal epithelial cellsNoUSA/Slovakia
Small Airway Epithelial Cell ModelNewcells BiotechRespiratorySmall airway (bronchiolar) epitheliumSmall airway epithelial cellsUK
KeraSkin-FT™BioSolutionSkinFull thickness thickness skin (epidermis & dermis) – KoreanPrimary human keratinocytes & fibroblastsSouth Korea
KeraSkin-M™BioSolutionSkinReconstructed epidermis (pigmented) – KoreanPrimary human keratinocytes & melanocytesSouth Korea
KeraSkin™BioSolutionSkinReconstructed epidermis (Korean)Primary human keratinocytesSouth KoreaTG 439
Skimune®Alcyomics®SkinFull thickness reconstructed skin tissue (explant) – dermis, epidermis; incl. Blood samplesFull thickness skin tissue (explant) incl. Peripheral Blood Mononuclear CellsUK
Skimune® EpiAlcyomics®SkinReconstructed epidermisPrimary human keratinocytesUKAlternative for TG 431 & TG 439
3D Innervated Skin ModelAlcyomics®SkinFull thickness reconstructed skin tissue (epidermis & dermis) incl. neuronsPrimary human keratinocytes & fibroblasts, incl. iPSC-derived Schwann cells & neuronsUK
Skimune 3D®Alcyomics®SkinFull thickness reconstructed skin tissue (epidermis & dermis)Primary human keratinocytes & fibroblastsUK
3D bioprintedAtlantis BioscienceSkinReconstructed epidermis (pigmented)Primary human keratinocytes, melanocytes, immune cells (macrophages), sebocytes & endothelial cellsSingapore
Adult human skin, full thicknessAtlantis BioscienceSkinFull thickness skin tissue (explant) – dermis, epidermisFull thickness skin tissue (explant)Singapore
Ex vivo explantsCreative BioarraySkinFull thickness skin tissue (explant) – dermis, epidermisFull thickness skin tissue (explant)USA/Germany
Full Thickness Skin ModelCreative BioarraySkinFull thickness reconstructed skin tissue (epidermis & dermis)Primary human keratinocytes & fibroblastsUSA/Germany
Neurodermatology Cell ModelCreative BioarraySkinFull thickness reconstructed skin tissue (epidermis & dermis) incl. sensory neuronsPrimary human keratinocytes, sensory neuronsUSA/Germany
Pigmented Skin ModelCreative BioarraySkinFull thickness reconstructed skin tissue (epidermis & dermis, pigmented)Primary human keratinocytes, fibroblasts & melanocytesUSA/Germany
Reconstructed Human EpidermisCreative BioarraySkinReconstructed epidermisPrimary human keratinocytesUSA/Germany
CTISkin®CTIBiotechSkinFull thickness skin tissue (explant) – dermis, epidermisFull thickness skin tissue (explant)Singapore
Sebocyte 3D modelCTIBiotechSkinHypodermis – Sebaceous glandSebocytesFrance
DNSKinFT™DeNova SciencesSkinFull thickness thickness skin (Asian)Primary human keratinocytes & fibroblastsYesSingapore
DNSkin™DeNova SciencesSkinReconstructed epidermis (Asian)Primary human keratinocytesYesSingapore
EpiSkin™ Human EpidermisEpiSkin, L’orealSkinReconstructed epidermisPrimary human keratinocytesFranceTG 431
SkinEthic™ RHE-LCEpiSkin, L’orealSkinReconstructed epidermis & LangerhansPrimary human keratinocytes & Langerhans cellsFrance
SkinEthic™ RHPEEpiSkin, L’orealSkinReconstructed epidermis (pigmented)Primary human keratinocytes & melanocytesFrance
SkinEthic™ RHEEpiSkin, L’orealSkinReconstructed epidermisPrimary human keratinocytesYesFranceTG 431, TG 439
T-Skin™EpiSkin, L’orealSkinFull thickness reconstructed skin tissue (epidermis & dermis)Primary human keratinocytes & fibroblastsFrance
NativeSkin®GenoskinSkinFull thickness skin tissue (explant) – dermis, epidermisFull thickness skin tissue (explant)YesFrance /USA
HypoSkin®GenoskinSkinFull thickness skin tissue (explant) – dermis, epidermis & hypodermis (adipose)Full thickness skin tissue (explant)YesFrance /USA
LabCyte EPI-MODELJapan Tissue EngineeringSkinReconstructed epidermisPrimary human keratinocytesNoJapanTG 431, TG 439
LabCyte EPI-MODEL 6DJapan Tissue EngineeringSkinReconstructed epidermisPrimary human keratinocytesNoJapan
3D ADIPOPrintLabskin CreationsSkinHypodermis tissue (adipose)Adipose stem cell-derived adipocytesFrance
3D PIGMENTSkinLabskin CreationsSkinFull thickness reconstructed skin tissue (epidermis & dermis, pigmented)Primary human keratinocytes, fibroblasts & melanocytesFrance
Bioprinted Human Pigmented EpidermisLabskin CreationsSkinReconstructed epidermis (pigmented)Primary human keratinocytes & melanocytesFrance
LabSkin Reconstructed Human EpidermisLabskin CreationsSkinReconstructed epidermisPrimary human keratinocytesFrance
3D SEBOSkinLabskin CreationsSkinFull thickness reconstructed skin tissue (epidermis & dermis) incl. sebaceous glandsPrimary human keratinocytes, fibroblasts & iPSC-derived sebocytesFrance
3D VASCULOSkinLabskin CreationsSkinFull thickness reconstructed skin tissue (epidermis & dermis) incl. endothelial cellsPrimary human keratinocytes, fibroblasts & endothelial cellsFrance
EpiDerm™MatTekSkinReconstructed epidermisPrimary human keratinocytesNoUSA/SlovakiaTG 431, TG 439, TG 498
EpiDerm™ FTMatTekSkinFull thickness reconstructed skin tissue (epidermis & dermis)Primary human keratinocytes & fibroblastsNoUSA/Slovakia
MelanoDerm™MatTekSkinReconstructed epidermis (pigmented) – Caucasian, African or AsianPrimary human keratinocytes & melanocytesNoUSA/Slovakia
Phenion® FT AGEDPhenionSkinFull thickness reconstructed skin tissue (epidermis & dermis) – senescentPrimary human keratinocytes & fibroblastsGermany
Phenion® FT LONG-LIFEPhenionSkinFull thickness reconstructed skin tissue (epidermis & dermis) – agedPrimary human keratinocytes & fibroblastsGermany
Phenion® FT Skin ModelPhenionSkinFull thickness reconstructed skin tissue (epidermis & dermis)Primary human keratinocytes & fibroblastsGermanyAlternative for TG439
Silabskin® FTSilabSkinFull thickness thickness skin (epidermis & dermis)Primary human keratinocytes & fibroblastsFrance
Silabskin® RESilabSkinReconstructed epidermisPrimary human keratinocytesFrance
Straticell RHEStratiCELLSkinReconstructed epidermisPrimary human keratinocytesBelgium
Straticell RHE-huSNStratiCELLSkinReconstructed epidermis & sensory neuronsPrimary human keratinocytes & iPSC-derived sensory neuronsBelgium
Straticell RHE-MELStratiCELLSkinReconstructed epidermis (pigmented)Primary human keratinocytes & melanocytesBelgium
Straticell adipose modelStratiCELLSkinHypodermis tissue (adipose)Human white pre-adipocytes, human differentiated white adipocytes, or immortalized mouse preadipocyte cells (3T3L1)Belgium
SkinEthic™ HVEEpiSkin, L’orealVaginaVaginal epitheliumImmortalized human vaginal epithelial cells (A431)YesFrance
EpiVaginal™MatTekVaginaVaginal epitheliumPrimary human ectocervical cells (custom: + dendritic cells)NoUSA/Slovakia
EpiVaginal™ FTMatTekVaginaVaginal epitheliumPrimary human ectocervical cells and fibroblasts (custom: + dendritic cells)NoUSA/Slovakia