NICEATM and Collaborators Publish Open-Source Integrated Testing Strategy for Skin Sensitization Potency

In a recent short communication to the journal ALTEX, NICEATM scientists and collaborators describe an open-source implementation of a previously published integrated testing strategy (ITS) for skin sensitization.  The ITS uses a Bayesian network to provide probabilistic predictions of skin sensitization potency based on in silico and in vitro information as well as skin penetration characteristics. The Bayesian network was designed to be consistent with the adverse outcome pathway published by the OECD. The short communication is available here. The data used to develop the ITS and a fully documented version of the R code for the ITS are available here.